Composite
Part:BBa_K777101:Design
Designed by: Team Goettingen Group: iGEM12_Goettingen (2012-09-19)
flhDC operon under the control of constitutive promoter J23100
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12INCOMPATIBLE WITH RFC[12]Illegal NheI site found at 7
Illegal NheI site found at 30 - 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal AgeI site found at 650
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
- The PstI restriction site in the flhDC sequence was mutated to CTGCGG using the reverse primer.
- flhDC was amplified from genomic DNA of E. coli DH10B via PCR using the following primers:
- Fwd: 5'-actgaattcgcggccgcttctagatgcatacctccgagttgctg-3'
- Rev: 5'-tcctgcagcggccgctactagttactgcccgggatggcggttgacataagcCgcaggcaaagctgccaacag-3'
(the capitalized "C" induces the mutation for removal of the PstI site)
Source
- The part was amplified from genomic DNA of E. coli str. K-12 substr. DH10B, complete genome (CP000948.1).
- J23100 information was taken from the parts.igem and physical DNA from the 2012 distribution kit.